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Effective treatments for Acute Kidney Injury

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Finding a solution to acute kidney injury

Acute kidney injury (AKI) is a serious complication that may affect over 30% of all critically ill patients e.g. with septicemia, septic shock or multiple traumas, as well as a considerable proportion of patients that have undergone cardiopulmonary bypass surgery. The annual incidence of new cases worldwide is in the order of 13 million, with a rising tendency. In addition, there is a further rise in patient numbers as a result of the COVID-19 pandemic. The market for an effective treatment, should one be found, is estimated to amount billions of USD.

Acute kidney injury factoid

Covid-19 and AKI

Patients with COVID-19, who were hospitalised between March 11 and April 26 2020, were twice as likely to develop AKI as compared to non-COVID patients who developed AKI during the same time period in 2019 – 56.9% versus 25.1% respectively.

Sudden AKI

AKI is a sudden episode of kidney failure or kidney damage that happens within a few hours or a few days.

Organs affected by AKI

AKI can also affect other organs such as the brain, heart, and lungs. AKI is common in patients who are in the hospital, in intensive care units, and especially in older adults.

AKI signs

Too little urine leaving the body, swelling, fatigue or tiredness, shortness of breath, confusion, nausea, seizures or coma in severe cases and chest pain or pressure. These are all signs of AKI however in some cases there are no symptoms at all.

Causes of AKI

Low blood pressure, shock, blood or fluid loss, organ failure, overuse of pain medicines, severe allergic reactions, burns, injury, major surgery, heart attack, heart failure, and other conditions leading to decreased heart function.

Future of AKI

Most people with acute kidney injury are already in the hospital for another reason. AKI Therapeutics are however developing a new treatment which will significantly decrease the time of recovery and efficiency of treatment.

Read about our treatment and AKI

Our Promise

Our patients health and safety is always our number one priority

Acute kidney injury (AKI) is a sudden episode of kidney failure or kidney damage that happens within a few hours or a few days. AKI causes a build-up of waste products in your blood and makes it hard for your kidneys to keep the right balance of fluid in your body. AKI can also affect other organs such as the brain, heart, and lungs. Acute kidney injury is common in patients who are in the hospital, in intensive care units, and especially in older adults.

After having AKI, your chances are higher for other health problems (such as kidney disease, stroke, heart disease) or having AKI again in the future. The chances for developing kidney disease and kidney failure increase every time AKI occurs. To protect yourself, you should follow up with your healthcare provider to keep track of your kidney function and recovery. The best ways to lower your chances of having kidney damage and to save kidney function are to prevent acute kidney injury or to find and treat it as early as possible.